产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

DRP-2 (P510) polyclonal antibody（KU）

货号: BS3005

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3005

Product Name :DRP-2 (P510) polyclonal antibody（KU）

Swiss-Prot :Q16555

Host :Rabbit

Reactivity :Human

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Dystrophin, utrophin and dystrophin-related protein 2 (DRP2) are Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin is expressed in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. Evidence suggests that the upregulation of utrophin (also known as DRP1) can reduce the dystrophic pathology. DRP2 is principally expressed in the brain and spinal cord. Analysis of DRP2 expression in rat brain on SDS-PAGE reveals a characteristic quartet of bands from 100-120 kDa. DRP2 exhibits a punctate staining pattern of rat neuronal dendrites and in neuropil. DRP2 forms a complex with dystroglycan at the surface of myelin-forming Schwann cells and may play a role in the terminal stages of myelinogenesis in the peripheral nervous system. The gene encoding human DRP2 maps to chromosome Xq22.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DRP-2 (P510) polyclonal antibody detects endogenous levels of DRP-2 protein.

BiowMW :~ 62 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Dihydropyrimidinase-related protein 2; DRP2; Collapsin response mediator protein 2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2; DPYSL2; CRMP2; ULIP2

Immunogen :Synthetic peptide, corresponding to amino acids 468-532 of Human DRP-2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DRP-2 (P510) pAb at 1:500 dilution Lane1:H1792 whole cell lysate(40ug) Lane2:SK-OVCAR3 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of DRP-2 (P510) pAb in paraffin-embedded human brain tissue .

Proteomic Changes in Female Rat Hippocampus Following Exposure to a Terrified Sound Stress

JournalJournal Of Molecular Neuroscience

ApplicationWB

IF3.444

SpeciesRat

PMID
Proteomics Reveals Intersexual Differences in the Rat Brain Hippocampus

JournalAnatomical Record

ApplicationWB

IF1.329

SpeciesRat

PMID23381953
Proteomic Analysis of Protein Expression Throughout Disease Progression in a Mouse Model of Alzheimer’s Disease

JournalJournal Of Alzheimers Disease

ApplicationWB

IF4.472

SpeciesMouse

PMID26401771