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DNAM-1 (Y325) polyclonal antibody

货号: BS2990

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2990

Product Name :DNAM-1 (Y325) polyclonal antibody

Swiss-Prot :Q15762

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:1000 IF: 1:50~1:200

Background :DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DNAM-1 (Y325) polyclonal antibody detects endogenous levels of DNAM-1 protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226; DNAM1

Immunogen :Synthetic peptide, corresponding to amino acids 293-342 of Human DNAM-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DNAM-1 (Y325) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate