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ICAM-1 (Q506) polyclonal antibody

货号: BS2980

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2980

Product Name :ICAM-1 (Q506) polyclonal antibody

Swiss-Prot :P05362

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase in inflammation. Also, ICAM1 is detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ICAM-1 (Q506) polyclonal antibody detects endogenous levels of ICAM-1 protein.

BiowMW :~ 89, 92 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD54; ICAM1

Immunogen :Synthetic peptide, corresponding to amino acids 471-520 of Human ICAM-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ICAM-1 (Q506) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(20ug) Lane2:A549 whole cell lysate(40ug) Lane3:H1792 whole cell lysate(40ug) Lane4:C6 whole cell lysate(40ug) Lane5:SP2/0 whole cell lysate(40ug)