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GPR10 (Q223) polyclonal antibody

货号: BS2958

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2958

Product Name :GPR10 (Q223) polyclonal antibody

Swiss-Prot :P49683

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:1000 IF: 1:50~1:200

Background :G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. G protein coupled receptor 10 (GPR10) acts as a receptor for prolactin-releasing peptide (PrRP). GPR10 plays a role in the regulation of food intake, pain-signal processing and in lactation. Primarily expressed in pituitary gland, it is repressed by bromocriptine. GPR10 interacts with various other proteins, including GRIP1, GRIP2 and PICK1.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GPR10 (Q223) polyclonal antibody detects endogenous levels of GPR10 protein.

BiowMW :~ 41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Prolactin-releasing peptide receptor; PrRP receptor; PrRPR; G-protein coupled receptor 10; hGR3; PRLHR; GR3

Immunogen :Synthetic peptide, corresponding to amino acids 200-250 of Human GPR10.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GPR10 (Q223) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Hela whole cell lysate Lane3:Rat brain tissue lysate