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CTPS (K109) polyclonal antibody（KU）

货号: BS2871

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2871

Product Name :CTPS (K109) polyclonal antibody（KU）

Swiss-Prot :P17812

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :CTPS (cytidine-5-prime-triphosphate synthase) is a 591 amino acid protein that contains one glutamine amidotransferase type-1 domain and is involved in pyrimidine metabolism. CTPS catalyzes the ATP-dependent conversion of UTP to CTP, a rate-limiting reaction that requires either ammonia or L-glutamine as a nitrogen source. Via its catalytic activity, CTPS plays an important role in the synthesis of nucleic acids and is crucial for proper cell growth and development. The function of CTPS is regulated by a variety of mechanisms, including phosphorylation by protein kinase C (PKC), an event that can either stimulate or inhibit CTPS activity. The gene encoding CTPS is located in a region on chromosome 1 that is often associated with the progression of several tumor types, suggesting a possible role for CTPS in tumorigenesis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CTPS (K109) polyclonal antibody detects endogenous levels of CTPS protein.

BiowMW :~ 67 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1; CTPS1; CTPS

Immunogen :Synthetic peptide, corresponding to amino acids 80-130 of Human CTPS.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CTPS (K109) pAb at 1:1000 dilution Lane1:The Kidney tissue lysate of Mouse(40ug) Lane2:The Kidney tissue lysate of Rat(40ug) Lane3:HEK293T whole cell lysate(10ug) Lane4:A549 whole cell lysate(10ug)

Immunohistochemistry (IHC) analyzes of CTPS (K109) pAb in paraffin-embedded liver cancer tissue at 1:100.