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Frizzled-5 (Y500) polyclonal antibody

货号: BS2795

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS2795

Product Name :Frizzled-5 (Y500) polyclonal antibody

Swiss-Prot :Q13467

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 5 protein is believed to be the receptor for the Wnt5A ligand. Frizzled 5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. Frizzled 5 was cloned from a retina cDNA library.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Frizzled-5 (Y500) polyclonal antibody detects endogenous levels of Frizzled-5 protein.

BiowMW :~ 65 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Wntβ catenin signaling，

Alternative Name :Frizzled 5; Frizzled5; Fz-5; hFz5; FzE5; FZD5; C2orf31

Immunogen :Synthetic peptide, corresponding to amino acids 468-519 of Human Frizzled-5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Frizzled-5 (Y500) pAb at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:MEF whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:HepG2 whole cell lysate(40ug) Lane5:K562 whole cell lysate(40ug)