产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

mGluR-5 (K56) polyclonal antibody（KU）

货号: BS2732

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2732

Product Name :mGluR-5 (K56) polyclonal antibody（KU）

Swiss-Prot :P41594

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :mGluR5 (K56) polyclonal antibody detects endogenous levels of mGluR5 protein.

BiowMW :~132 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Metabotropic glutamate receptor 5; mGluR5; GRM5; GPRC1E; MGLUR5

Immunogen :Synthetic peptide, corresponding to amino acids 30-80 of Human mGluR-5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of mGluR-5 (K56) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(10ug) Lane4:SK-OVCAR3 whole cell lysate(40ug) Lane5:L02 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of mGluR-5 (K56) pAb in paraffin-embedded human esophageal carcinoma tissue at 1:50.showing cell membrane staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B

JournalScientific Reports

ApplicationWB

IF4.379

SpeciesMouse

PMID24413569