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Glucagon Receptor (K136) polyclonal antibody（KU）

货号: BS2718

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2718

Product Name :Glucagon Receptor (K136) polyclonal antibody（KU）

Swiss-Prot :P47871

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:1000 IF: 1:50~1:200

Background :Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Glucagon Receptor (K136) polyclonal antibody detects endogenous levels of Glucagon Receptor protein.

BiowMW :~ 54 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Glucagon receptor; GL-R; GCGR

Immunogen :Synthetic peptide, corresponding to amino acids 100-150 of Human Glucagon Receptor.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Glucagon Receptor (K136) polyclonal antibody at 1:500 dilution Lane1:AML-12 whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:HEK293T whole cell lysate(40ug)