Product Name :GPR171 (T180) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :IHC: 1:50~1:200
IF: 1:50~1:200
Background :G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. G protein-coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. GPR171, also designated H963, is a 319 amino acid protein that is structurally related to the purinergic receptors P2Y12, P2Y13 and P2Y14.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :GPR171 (T180) polyclonal antibody detects endogenous levels of GPR171 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Probable G-protein coupled receptor 171; G-protein coupled receptor H963
Immunogen :Synthetic peptide, corresponding to amino acids 151-200 of Human GPR171.
Modification :Unmodification
