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GCN5 (G720) polyclonal antibody

货号: BS2669

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2669

Product Name :GCN5 (G720) polyclonal antibody

Swiss-Prot :Q92830

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC:1:50~1:200

Background :KAT2A / GCN5 is a transcriptional co-activator that has histone acetyltransferase activity. It exhibits significant histone acetyltransferase activity with core histones but not with nucleosome core particles. KAT2A is a component of the TFTC-HAT and STAGA complexes. KAT2A is also recruited by the viral protein Tat during HIV infection, inducing chromatin remodelling of proviral genes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GCN5 (G720) polyclonal antibody detects endogenous levels of GCN5 protein.

BiowMW :~ 100 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Epigenetic Writers and Erasers of Histone H3,Epigenetic Writers and Erasers of Histones H2A H2B and H4,

Alternative Name :Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97; KAT2A; GCN5; GCN5L2; HGCN5

Immunogen :Synthetic peptide, corresponding to amino acids 685-740 of Human GCN5.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of GCN5 (G720) pAb in paraffin-embedded human colon carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells

JournalCancer Letters

ApplicationWB

IF6.508

SpeciesHuman

PMID28455245