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DPF2 (E174) polyclonal antibody（KU）

货号: BS2668

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2668

Product Name :DPF2 (E174) polyclonal antibody（KU）

Swiss-Prot :Q92785

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :DPF2 (D4, zinc and double PHD fingers family 2), also known as REQ (Requiem), UBID4 or ubi-d4, is a 391 amino acid protein that is a member of the D4 domain family. DPF2, a ubiquitously expressed protein, localizes to the nucleus and contains one C2H2- and two PHD-type zinc finger motifs. DPF2 may function as a transcription factor that is necessary for apoptosis and may also play a role in the development and maturation of lymphoid cells. It is thought that, during apoptosis, DPF2 activity is inhibited by LRF (Leukemia/lymphoma-related factor), which is upregulated by integrin. This suggests that DPF2 may be a potential target for future cancer therapies that induce apoptosis in leukemia cells. Alternative splicing of this gene generates multiple isoforms lacking certain domain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DPF2 (E174) polyclonal antibody detects endogenous levels of DPF2 protein.

BiowMW :~ 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4; D4 zinc and double PHD fingers family 2; double PHD fingers family 2; DPF 2; DPF2; MGC10180; Protein requiem; REQ; REQU; Requiem; Requiem apoptosis response zinc finger; UBI D4; ubi-d4; UBID 4; UBID4; zinc and double PHD fingers family 2; Zinc finger protein ubi d4;

Immunogen :Synthetic peptide, corresponding to amino acids 140-188 of Human DPF2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of DPF2 (E174) polyclonal antibody at 1:1000 dilution Lane1:THP-1 whole cell lysate(37ug) Lane2:MCF-7 whole cell lysate(48ug) Lane3:RAW264.7 whole cell lysate(57ug) Lane4:NIH3T3 whole cell lysate(48ug) Lane5:H9C2 whole cell lysate(37ug)