Product Name :HoxD12 (E230) polyclonal antibody（KU）
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
Background :The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :HoxD12 (E230) polyclonal antibody detects endogenous levels of HoxD12 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Homeobox protein Hox-D12; Homeobox protein Hox-4H; HOXD12; HOX4H
Immunogen :Synthetic peptide, corresponding to amino acids 200-250 of Human HoxD12.
Modification :Unmodification
