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EMR2 (L160) polyclonal antibody（KU）

货号: BS2617

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2617

Product Name :EMR2 (L160) polyclonal antibody（KU）

Swiss-Prot :Q9UHX3

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :EMR2 is a member of the EGF-TM7 receptor subfamily. EGF-TM7 receptors are a family of class B, seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system. Within the TM7 superfamily, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique. Derived from the processing of a single polypeptide, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety. Through a variable number of N-terminal EGF-like domains, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate. EMR2 is a heptahelical molecule predominantly expressed on cells of the immune system such as leukocytes. EMR2 is proteolytically cleaved into two separate subunits: a seven-transmembrane subunit, and an extracellular α subunit.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :EMR2 (L160) polyclonal antibody detects endogenous levels of EMR2 protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module receptor 2; CD312

Immunogen :Synthetic peptide, corresponding to amino acids 130-178 of Human EMR2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of EMR2 (L160) pAb at 1:500 dilution Lane1:K562 whole cell lysate(40ug) Lane2:U-87MG whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:The Lung tissue lysate of Mouse(40ug) Lane5:The Lung tissue lysate of Rat(40ug)