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Gas6 (G309) polyclonal antibody

货号: BS2563

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2563

Product Name :Gas6 (G309) polyclonal antibody

Swiss-Prot :Q14393

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Gas6 (G309) polyclonal antibody detects endogenous levels of Gas6 protein.

BiowMW :~ 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; AXLLG; GAS6

Immunogen :Synthetic peptide, corresponding to amino acids 278-328 of Human Gas6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Gas6 (G309) polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Mouse heart tissue lysate Lane3:PC12 whole cell lysate

Immunohistochemistry (IHC) analyzes of Gas6 (G309) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6

JournalJournal Of Biological Chemistry

ApplicationELISA, WB

IF4.238

SpeciesHuman

PMID28154173
Growth arrest‐specific 6 modulates adiponectin expression and insulin resistance in adipose tissue

JournalJournal of Diabetes Investigation

ApplicationWB

IF3.761

SpeciesHuman, Mouse

PMID32969596