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EphB6 (D881) polyclonal antibody

货号: BS2450

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2450

Product Name :EphB6 (D881) polyclonal antibody

Swiss-Prot :O15197

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :EphB6 (D881) polyclonal antibody detects endogenous levels of EphB6 protein.

BiowMW :~ 119 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ephrin type-B receptor 6; HEP; Tyrosine-protein kinase-defective receptor EPH-6; EPHB6

Immunogen :Synthetic peptide, corresponding to amino acids 851-900 of Human EphB6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of EphB6 (D881) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:PC12 whole cell lysate Lane4:H9C2 whole cell lkysate

Immunohistochemistry (IHC) analyzes of EphB6 (D881) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.showing secreted and cell membrane staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.