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ERβ (E101) polyclonal antibody

货号: BS2429

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2429

Product Name :ERβ (E101) polyclonal antibody

Swiss-Prot :Q92731

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:1000 IF: 1:50~1:200

Background :Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ER-β (E101) polyclonal antibody detects endogenous levels of ER-β protein.

BiowMW :~ 48, 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2; ESR2; ESTRB; NR3A2; ER-β

Immunogen :Synthetic peptide, corresponding to amino acids 71-120 of Human ERβ.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ERβ (E101) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:H9C2 whole cell lysate

Estrogen Receptor and PI3K/Akt Signaling Pathway Involvement in S-(-)Equol-Induced Activation of Nrf2/ARE in Endothelial Cells

JournalPLoS One

ApplicationIF

IF2.776

SpeciesHuman

PMID24260155
GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells

JournalMolecular And Cellular Biochemistry

ApplicationWB

IF2.884

SpeciesHuman

PMID26541755
Which play a more important role in the development of large-sized prostates (≥80 ml), androgen receptors or oestrogen receptors? A comparative study

JournalInternational Urology And Nephrology

ApplicationWB

IF1.596

SpeciesHuman

PMID26685888
Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERα levels

JournalBiochimica Et Biophysica Acta-General Subjects

ApplicationWB

IF3.77

SpeciesHuman

PMID34743989