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Elongin A3 (E403) polyclonal antibody

货号: BS2412

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2412

Product Name :Elongin A3 (E403) polyclonal antibody

Swiss-Prot :Q8NG57

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The elongin (SIII) complex is composed of a transcriptionally active A subunit and two small regulatory subunits, B and C. This complex stimulates the transcription elongation rate of RNA polyermase II by suppressing time spent at template-encoded arresting sites along DNA. Elongin A3, also known as RNA polymerase II transcription factor SIII subunit A3 and Transcription elongation factor B polypeptide 3C, is a 546 amino acid nuclear protein that functions as a general transcription elongation factor that increases RNA polymerase II transcription elongation and forms a stable complex with Elongin BC. In contrast to Elongin A, transcriptional activity of Elongin A3 is not stimulated by Elongin BC. Elongin A3 contains one TFIIS N-terminal domain and is ubiquitously expressed in human tissue.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Elongin A3 (E403) polyclonal antibody detects endogenous levels of Elongin A3 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TCEB3C; Elongin-A3; Elongin A3; ElonginA3; EloA3; TCEB3L2

Immunogen :Synthetic peptide, corresponding to amino acids 370-422 of Human Elongin A3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Elongin A3 (E403) polyclonal antibody at 1:500 dilution Lane1:Jurkat cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat kidney tissue lysate