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FUK (Q26) polyclonal antibody（KU）

货号: BS2330

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2330

Product Name :FUK (Q26) polyclonal antibody（KU）

Swiss-Prot :Q8N0W3

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Blood group antigen recognition, metastasis and inflammation utilize fucose, a sugar found in glycoproteins and glycolipids. Fucokinase, also designated L-fucose kinase or FUK, is a 1,084 amino acid enzyme that plays a role in the salvage pathway of fucose reutilization. A member of the GHMP kinase family, Fucokinase exists as two alternative splice variants and catalyzes L-fucose phosphorylation to form β-L-fucose 1-phosphate. The gene encoding Fucokinase maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn’s disease, which is a gastrointestinal inflammatory condition.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Fucokinase (Q26) polyclonal antibody detects endogenous levels of Fucokinase protein.

BiowMW :~ 118 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :L-fucose kinase; Fucokinase; FUK

Immunogen :Synthetic peptide, corresponding to amino acids 10-70 of Human Fucokinase.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Fucokinase (Q26) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(30ug) Lane2:PC12 whole cell lysate(40ug) Lane3:Beas-2B whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)