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C/EBP ζ (D24) polyclonal antibody（KU）

货号: BS2297

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2297

Product Name :C/EBP ζ (D24) polyclonal antibody（KU）

Swiss-Prot :Q03701

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :C/EBP family members include C/EBP α, C/EBP β, C/EBP γ, C/EBP δ, C/EBP ε and C/EBP ζ, all of which are capable of forming homodimers or heterodimers with each other. C/EBP ζ, also known as CBF2, NOC1, CHOP10 (C/EBP homologous protein 10), GADD153 (growth arrest and DNA damage-inducible gene 153) or HSPCBF, is a ubiquitously expressed 1,054 amino acid protein that localizes to the nucleus and regulates transcription. More specifically, C/EBP ζ is believed to play a role regulating the expression of CRP (C-reactive protein). Unlike most C/EBP dimers, C/EBP ζ-containing dimers do not bind the classical C/EBP-binding consensus sequence. Rather, C/EBP ζ-containing dimers must associate with RBP-Jκ (another transcription factor) in order to accomplish binding to the C/EBP site.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :C/EBP ζ (D24) polyclonal antibody detects endogenous levels of C/EBP ζ protein.

BiowMW :~121 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBF2; CCAAT binding factor; CCAAT box binding transcription factor; CCAAT/enhancer binding protein zeta; Cebpz; HSPCBF; CBF;

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human C/EBP ζ.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of C/EBP ζ (D24) pAb at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:3T3-L1 whole cell lysate(40ug) Lane3:A2780 whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug) Lane5:MCF-7 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of C/EBP ζ (D24) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.