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FXR2 (E576) polyclonal antibody（KU）

货号: BS2008

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS2008

Product Name :FXR2 (E576) polyclonal antibody（KU）

Swiss-Prot :P51116

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF IP

Application_all :WB: 1:500~1:1000 IHC/IF: 1:50~1:200 IP: 1:10~1:100

Background :The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 can also interact with two fragile X syndrome related factors, FXR1 and FXR2, and these proteins form heterodimers through their N-terminal coilcoiled domains. FMR1 localizes to both the nucleus and the cytoplasm, and since it contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleo-cytoplasmic transport of mRNAs.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FXR2 (E576) polyclonal antibody detects endogenous levels of FXR2 protein.

BiowMW :~ 74 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fragile X mental retardation syndrome-related protein 2; FMR1L2; FXR2

Immunogen :Synthetic peptide, corresponding to amino acids 550-600 of Human FXR2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of FXR2 (E576) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:K562 whole cell lysate(40ug) Lane3:H9C2 whole cell lysate(40ug) Lane4:MEF whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of FXR2 (E576) pAb in paraffin-embedded human colon carcinoma tissue at 1:50,showing cytoplasmic and nuclear staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Immunoprecipitation of HEK293T cell lysate using FXR2 (E576) pAb (Sepharose Bead Conjugate) #BD0048(lane 2 and lane 3) .Lane 1 is 30% input. The western blot was probed using FXR2 (E576) #BS2008.“↑”（supernatant）; “↓(deposition）