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GATA4 (R306) polyclonal antibody

货号: BS1998

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1998

Product Name :GATA4 (R306) polyclonal antibody

Swiss-Prot :P43694

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :GATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GATA4 (R306) polyclonal antibody detects endogenous levels of GATA4 protein.

BiowMW :~ 46 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :ESC Pluripotency and Differentiation Signaling Pathway,

Alternative Name :Transcription factor GATA-4; GATA-binding factor 4; GATA4; GATA 4

Immunogen :Synthetic peptide, corresponding to amino acids 280-320 of Human GATA4.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of GATA4 (R306) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

免疫沉淀（IP）

免疫组织化学（IHC）