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DGK-α (A340) polyclonal antibody（KU）

货号: BS1960

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1960

Product Name :DGK-α (A340) polyclonal antibody（KU）

Swiss-Prot :P23743

Host :Rabbit

Reactivity :Human,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-alpha influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-beta is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-gamma encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-delta is most abundant in skeletal muscle. DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol and is expressed predominantly in testis. DGK-zeta is most abundant in brain and muscle. DGK-eta is closely related to DGK-delta. DGK-theta is most abundant in the cerebellum and hippocampus.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DGK-α (A340) polyclonal antibody detects endogenous levels of DGK-α protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Diacylglycerol kinase alpha; DAG kinase alpha; 80 kDa diacylglycerol kinase; Diglyceride kinase alpha; DGK-alpha; DGKA; DAGK; DAGK1

Immunogen :Synthetic peptide, corresponding to amino acids 310-360 of Human DGK-α.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DGK-α (A340) pAb at 1:2000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:U-87MG whole cell lysate(40ug) Lane3:Myla2059 whole cell lysate(40ug) Lane4:HuT78 whole cell lysate(10ug)

Immunohistochemistry (IHC) analyzes of DGK-α (A340) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.