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HKR1 (W154) polyclonal antibody（KU）

货号: BS1923

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1923

Product Name :HKR1 (W154) polyclonal antibody（KU）

Swiss-Prot :P10072

Host :Rabbit

Reactivity :Humam

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HKR1 (W154) polyclonal antibody detects endogenous levels of HKR1 protein.

BiowMW :~ 73 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Krueppel-related zinc finger protein 1; Protein HKR1; Zinc finger protein 875; HKR1; ZNF875

Immunogen :Synthetic peptide, corresponding to amino acids 111-160 of Human HKR1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HKR1 (W154) pAb at 1:1000 dilution Lane1:HEK293T whole cell lysate(20ug) Lane2:A549 whole cell lysate(40ug) Lane3:PC3 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of HKR1 (W154) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.