产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

APRIL (S183) polyclonal antibody（KU）

货号: BS1893

价格：￥ 660

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1893

Product Name :APRIL (S183) polyclonal antibody（KU）

Swiss-Prot :O75888

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :A proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :APRIL (S183) polyclonal antibody detects endogenous levels of APRIL protein.

BiowMW :~ 22 to 32 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; TRDL1; CD256; TNFSF13; APRIL; TALL2; ZTNF2; ORF Names: UNQ383/PRO715

Immunogen :Synthetic peptide, corresponding to amino acids 151-200 of Human APRIL.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of APRIL (S183) pAb at 1:500 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:Panc1 whole cell lysate(40ug) Lane4:H9C2 whole cell lysate(40ug) Lane5:CT26 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of APRIL (S183) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.