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GRB10 (L63) polyclonal antibody

货号: BS1748

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1748

Product Name :GRB10 (L63) polyclonal antibody

Swiss-Prot :Q13322

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC IF

Application_all :IHC: 1:50~1:200 IF: 1:50~1:200

Background :GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GRB10 (L63) polyclonal antibody detects endogenous levels of GRB10 protein.

BiowMW :~ 60 to 67 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Translational Contral elF4 and p70 S6 Kinase,

Alternative Name :Growth factor receptor-bound protein 10; GRB10 adapter protein; Insulin receptor-binding protein Grb-IR; GRB10; GRBIR; KIAA0207

Immunogen :Synthetic peptide, corresponding to amino acids 32-84 of Human GRB10.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of GRB10 (L63) pAb in paraffin-embedded human brain carcinoma tissue at 1:50.

免疫沉淀（IP）

免疫组织化学（IHC）