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AQP2 (R252) polyclonal antibody（KU）

货号: BS1718

价格：￥ 660

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1718

Product Name :AQP2 (R252) polyclonal antibody（KU）

Swiss-Prot :P41181

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AQP2 (R252) polyclonal antibody detects endogenous levels of AQP2 protein.

BiowMW :~ 26 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Aquaporin-2; AQP-2; ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct; AQP2

Immunogen :Synthetic peptide, corresponding to amino acids 230-280 of Human AQP2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of AQP2 (R252) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40µg) Lane2:Hela whole cell lysate(40µg) Lane3:The Kidney tissue lysate of Rat(40µg) Lane4:CT-26 whole cell lysate(40µg)

Immunohistochemistry (IHC) analyzes of AQP2 (R252) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.