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COXII polyclonal antibody

货号: BS1653

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1653

Product Name :COXII polyclonal antibody

Swiss-Prot :Q7JCZ1

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general “housekeeping” functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs .

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COXII polyclonal antibody detects endogenous levels of COXII protein.

BiowMW :~ 26 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cytochrome c oxidase polypeptide 2; Cytochrome c oxidase subunit 2; Cytochrome c oxidase subunit II; Cytochrome oxidase subunit 2; mt-Co2; Co2; COII; COX2; Cox2; COXII

Immunogen :A synthetic peptide corresponding to amino acids 49-63 of Mouse COXII.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of COXII polyclonal antibody at 1:1000 dilution Lane1:HepG-2 whole cell lysate(50μg) Lane2:The muscle tissue lysate of Mouse(33μg)

Dehydrocostus Lactone Inhibits Microglia-Mediated Neuroinflammation by Targeting CYP2A6 to Improve Ischemic Brain Injury

JournalCNS Neuroscience & Therapeutics

ApplicationWB

IF5

SpeciesMouse

PMID40616345