Product Name :GATA4 (Q258) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :IHC: 1:50~1:200
Background :GATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :GATA4 (Q258) polyclonal antibody detects endogenous levels of GATA4 protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :ESC Pluripotency and Differentiation Signaling Pathway,
Alternative Name :Transcription factor GATA-4; GATA-binding factor 4; GATA4; GATA 4
Immunogen :Synthetic peptide, corresponding to amino acids 230-280 of Human GATA4.
Modification :Unmodification
