Product Name :Doublecortin (K292) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :IHC: 1:50~1:200
Background :The DCDC2 gene encodes the DCDC2 protein (Doublecortin-containing protein 2, RU2, RU2S) which contains two Doublecortin peptide domains similar to those in the Doublecortin gene. DCDC2 is transcribed as a “normal” gene, which results in a sense transcript (RU2S), but when it is transcribed in the opposite direction, a shorter antisense transcript (RU2AS), which is found in tumors, results. The DCDC2 protein demonstrates ubiquitous expression, whereas RU2AS expression is restricted to normal kidney, bladder, liver, testis and tumors of various histologic origins. The deduced DCDC2 protein contains 476 amino acids, while the RU2AS protein contains 84 residues. There is a significant association between dyslexia and several SNPs within the DCDC2 gene.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Doublecortin (K292) polyclonal antibody detects endogenous levels of Doublecortin protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Neuronal and Glial Cell Marker Atlas,
Alternative Name :Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X; DCX; DBCN; LISX
Immunogen :Synthetic peptide, corresponding to amino acids 271-320 of Human Doublecortin.
Modification :Unmodification
