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HYD (T14) polyclonal antibody（KU）

货号: BS1460

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1460

Product Name :HYD (T14) polyclonal antibody（KU）

Swiss-Prot :O95071

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :EDD (for E3 identified by Differential Display) is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HYD (T14) polyclonal antibody detects endogenous levels of HYD protein.

BiowMW :~ 309 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein; UBR5; EDD; EDD1; HYD; KIAA0896

Immunogen :Synthetic peptide, corresponding to amino acids 1-50 of Human HYD.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HYD (T14) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:HK-2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of HYD (T14) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.