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mGluR-6 (A865) polyclonal antibody

货号: BS1146

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1146

Product Name :mGluR-6 (A865) polyclonal antibody

Swiss-Prot :O15303

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :mGluR6 (A865) polyclonal antibody detects endogenous levels of mGluR6 protein.

BiowMW :~ 100 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F; MGLUR6

Immunogen :Synthetic peptide, corresponding to amino acids 841-890 of Human mGluR-6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of mGluR-6 (A865) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:Raw264.7 cell lysate Lane4:H9C2 cell lysate

Immunohistochemistry (IHC) analyzes of mGluR-6 (A865) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.