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Galectin-3 (N174) polyclonal antibody（KU）

货号: BS1137

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1137

Product Name :Galectin-3 (N174) polyclonal antibody（KU）

Swiss-Prot :P17931

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. galectin-3 mediates the endocytosis of β-1 Integrins in a lactose-dependant manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Galectin-3 (N174) polyclonal antibody detects endogenous levels of Galectin-3 protein.

BiowMW :~ 30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBP35; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; Laminin-binding protein; Lectin L-29; Mac-2 antigen; LGALS3; MAC2; Galectin 3; Galectin3

Immunogen :Synthetic peptide, corresponding to amino acids 140-190 of Human Galectin-3.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Galectin-3 (N174) polyclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:HepG2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Galectin-3 (N174) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Immunofluorescence analysis of A549 cells using Galectin-3 (N174) pAb at dilution of 1:200 (40x lens).