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G3BP-1 (D226) polyclonal antibody（KU）

货号: BS1132

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1132

Product Name :G3BP-1 (D226) polyclonal antibody（KU）

Swiss-Prot :Q13283

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :G3BP-1 (D226) polyclonal antibody detects endogenous levels of G3BP-1 protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1

Immunogen :Synthetic peptide, corresponding to amino acids 196-246 of Human G3BP-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of G3BP-1 (D226) polyclonal antibody at 1:500 dilution Lane1:A549 cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat heart tissue lysate

Immunohistochemistry (IHC) analyzes of G3BP-1 (D226) pAb in paraffin-embedded human lymphoma tissue.