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FOSL2 (S301) polyclonal antibody（KU）

货号: BS1131

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1131

Product Name :FOSL2 (S301) polyclonal antibody（KU）

Swiss-Prot :P15408

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B, which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FOSL2 (S301) polyclonal antibody detects endogenous levels of FOSL2 protein.

BiowMW :~ 30-43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fos-related antigen 2; FRA-2; FOSL2; FRA2

Immunogen :Synthetic peptide, corresponding to amino acids 270-320 of Human FOSL2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of FOSL2 (S301) pAb at 1:500 dilution Lane1:The Ovary tissue lysate of Rat(40ug) Lane2:The Testis tissue lysate of Mouse(40ug) Lane3:PC3 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of FOSL2 (S301) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.