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E2F4/E2F5 (L50/83) polyclonal antibody

货号: BS1095

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1095

Product Name :E2F4/E2F5 (L50/83) polyclonal antibody

Swiss-Prot :Q16254/Q15329

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an “active” E2F transcriptional regulatory complex.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :E2F4/E2F5 (L50/83) polyclonal antibody detects endogenous levels of E2F4/E2F5 protein.

BiowMW :~ 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Cell Cycle Control G1 S Checkpoint,

Alternative Name :Transcription factor E2F4; E2F-4; E2F4; Transcription factor E2F5; E2F-5; E2F5

Immunogen :Synthetic peptide, corresponding to amino acids 18-72 of Human E2F4.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of E2F4/E2F5 (L50/83) pAb in paraffin-embedded human lung carcinoma tissue.

miRNA-154-5p Inhibits Proliferation, Migration and Invasion by Targeting E2F5 in Prostate Cancer Cell Lines

JournalUrologia Internationalis

ApplicationWB

IF2.089

SpeciesHuman

PMID27074041