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Claudin-11 (S198) polyclonal antibody

货号: BS1065

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1065

Product Name :Claudin-11 (S198) polyclonal antibody

Swiss-Prot :O75508

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Claudin 11 (S198) polyclonal antibody detects endogenous levels of Claudin 11 protein.

BiowMW :~ 24 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CLDN11; CLAUDIN-11; OSP; OTM; Claudin 11; Claudin11

Immunogen :Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-11.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Claudin-11 (S198) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:Rat heart tissue lysate

The Protective Effects Of Icariin Against Testicular Dysfunction In Type 1 Diabetic Mice Via AMPK-Mediated Nrf2 Activation And NF-κB p65 Inhibition

JournalPHYTOMEDICINE

ApplicationWB

IF7.9

SpeciesMouse

PMID37992492