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Bak (A2) polyclonal antibody（KU）

货号: BS1029

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1029

Product Name :Bak (A2) polyclonal antibody（KU）

Swiss-Prot :Q16611

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Bak or Bcl2 homologous antagonist is a member of the Bcl2 family of proteins. The Bcl-2 related proteins interact with one another through the formation of homo and heterodimers. The susceptibility of cells to apoptotic stimuli is thought to be controlled by the relative ratios of the different Bcl2 family proteins. Bak has been demonstrated to accelerate the rate of apoptosis in growth factor deprived murine lymphoid, neuronal and fibroblastic cell lines. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Bak (A2) polyclonal antibody detects endogenous levels of Bak protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7; BAK1; BAK; BCL2L7; CDN1

Immunogen :Synthetic peptide, corresponding to the N-terminal of Human Bak.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Bak (A2) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:Rat kidney tissue lysate

Immunohistochemistry (IHC) analyzes of Bak (A2) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Panax Notoginseng Saponins Attenuate Oxidative Stress-mediated Platelet Apoptosis in Hyperlipidemic Conditions via Up-regulating cAMP/PKA Signaling Pathway in vitro and in vivo

JournalJournal of Future Foods

ApplicationWB

IF7.2

SpeciesHuman

PMID