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GFAP (phospho-Ser38) polyclonal antibody（KU）

货号: AP0149

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :AP0149

Product Name :GFAP (phospho-Ser38) polyclonal antibody（KU）

Swiss-Prot :P14136

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Glial fibrillary acidic protein, or GFAP, is an intermediate filament (IF) protein belonging to the type III subclass of IF proteins. Like other IF proteins, GFAP is composed of an amino-terminal head domain, a central rod domain and a carboxy-terminal tail domain. GFAP is specifically found in astroglia, a cell type which is highly responsive to neurologic insults. Astrogliosis is found to be a result of mechanical trauma, AIDS dementia, prion infection and inflammatory demylination diseases, and is accompanied by an increase in GFAP expression. GFAP is an immunohistochemical marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-GFAP(Ser38) polyclonal antibody detects endogenous levels of GFAP protein when phosphorylated at Ser38.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,

Alternative Name :Glial fibrillary acidic protein

Immunogen :Synthetic phosphopeptide derived from human GFAP around the phosphorylation site of Serine 38.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-GFAP (Ser38) pAb at 1:500 dilution Lane1:The Brain tissue lysate of Rat (30ug) Lane2:The Brain tissue lysate of Mouse (40ug)