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DTX2 polyclonal antibody

货号: BS8881

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS8881

Product Name :DTX2 polyclonal antibody

Swiss-Prot :Q86UW9

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DTX2 polyclonal antibody detects endogenous levels of DTX2 protein.

BiowMW :~ 67kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; Deltex2; hDTX2; RING finger protein 58; DTX2; KIAA1528; RNF58

Immunogen :Recombinant full length Human DTX2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using DTX2 antibody.

Immunohistochemical analysis of p16 INK4a staining in human colorectal cancer formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）

免疫组织化学（IHC）