产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

HDAC5 polyclonal antibody

货号: BZ16439

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ16439

Product Name :HDAC5 polyclonal antibody

Swiss-Prot :Q9UQL6

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-F,IHC-P,ICC/IF,ELISA

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background :Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 122 kDa; Observed MW: 122 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HD5; NY-CO-9

Immunogen :The antiserum was produced against synthesized peptide derived from human HDAC5. AA range:464-513

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HDAC5 in various lysates using HDAC5 antibody.

Western blot analysis of HDAC5 in K562 lysates using HDAC5 antibody.