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HIF1β/ARNT polyclonal antibody

货号: BS77038

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS77038

Product Name :HIF1β/ARNT polyclonal antibody

Swiss-Prot :P27540

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:200

Background :This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARNT;HIF-1-beta;HIF-1beta;HIF1-beta;HIF1B;HIF1BETA;TANGO;bHLHe2

Immunogen :Recombinant fusion protein of human HIF1β/ARNT(NP_001659.1).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of H9C2 cells using HIF1β/ARNT Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of NIH-3T3 cells using HIF1β/ARNT Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U-S OS cells using HIF1β/ARNT Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.

免疫沉淀（IP）