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HMGB1 polyclonal antibody

货号: BS7131

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7131

Product Name :HMGB1 polyclonal antibody

Swiss-Prot :P09429

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background :High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFκB family to activate transcription.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HMGB1 polyclonal antibody detects endogenous levels of HMGB1 protein.

BiowMW :~25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1

Immunogen :Recombinant full length Human HMGB1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HMGB1 polyclonal antibody

Immunohistochemistry (IHC) analysis of HMGB1 polyclonal antibody in paraffin-embedded Human Embryo Brain tissue.

QRICH1, as a key effector of endoplasmic reticulum stress, enhances HBV in promoting HMGB1 translocation and secretion in hepatocytes

JournalIMMUNOBIOLOGY

ApplicationIHC

IF2.5

SpeciesMouse

PMID40383084