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ASAH1 polyclonal antibody

货号: BS66235

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66235

Product Name :ASAH1 polyclonal antibody

Swiss-Prot :Q13510

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF/ICC

Application_all :WB: 1:500~1:2000 IF/ICC: 1:50~1:200

Background :This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ASAH1 polyclonal antibody detects endogenous levels of ASAH1 protein.

BiowMW :~ 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AC; PHP; ASAH; PHP32; ACDase; SMAPME; ASAH1

Immunogen :Recombinant fusion protein of human ASAH1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of lysates from RT4 cells using ASAH1 pAb at 1:700 dilution.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）