Product Name :PIT1 Recombinant Rabbit mAb (KU)
Swiss-Prot :Q00286, P10037
Applications :WB, IHC, FC, IP
Background :Enables DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and sequence-specific DNA binding activity. Acts upstream of or within several processes, including determination of adult lifespan; positive regulation of cellular biosynthetic process; and somatotropin secreting cell development. Located in nucleus. Is expressed in several structures, including eye; genitourinary system; pituitary gland; and trunk somite. Human ortholog(s) of this gene implicated in panhypopituitarism and pituitary gland disease. Orthologous to human POU1F1 (POU class 1 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]
