Product Name :MASP1 Recombinant Rabbit mAb (KU)
Applications :WB,ICC/IF,FC
Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Background :This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification&Purity :Affinity Purified
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BiowMW :Calculated MW: 45 kDa; Observed MW: 45 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PGKA; MIG10; HEL-S-68p
Immunogen :A synthesized peptide derived from human PGK1
