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ATM Recombinant Rabbit mAb (KU)

货号: BS45565

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45565

Product Name :ATM Recombinant Rabbit mAb (KU)

Swiss-Prot :Q13315

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC,IP,ChIP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100 ChIP: 1/20

Background :The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 52 kDa; Observed MW: 52,60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SMAD2; MADH2; MADR2; Mothers against decapentaplegic homolog 2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2

Immunogen :Recombinant protein of human Smad2

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of Smad2/3 in HT-1080 using Smad2/3 antibody,and DAPI.