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Beclin 1 polyclonal antibody（KU）

货号: AP0768

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :AP0768

Product Name :Beclin 1 polyclonal antibody（KU）

Swiss-Prot :Q14457

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF

Application_all :WB,1:500 - 1:2000|IF,1:50 - 1:200

Background :This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :60KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATG6;VPS30;beclin1;Beclin 1;BECN1;beclin-1

Immunogen :Recombinant fusion protein of human Beclin 1(NP_003757.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Beclin 1 polyclonal antibody at 1:1000 dillution Lane1:U-87MG whole cell lysate(40μg) Lane2:MCF-7 whole cell lysate(40μg) Lane3:CT26 whole cell lysate(40μg) Lane4:PC12 whole cell lysate(40μg)

Immunofluorescence analysis of U-87MG cells using Beclin 1 antibody at dilution of 1:50.

miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice

JournalNEUROCHEMICAL RESEARCH

ApplicationWB

IF3.8

SpeciesMouse

PMID40471451